Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Dimethylamine | HCID 674 | — |
| Reactant | Tetrahydrofuran | HCID 8028 | — |
| Reactant | Pyridine, 2-methyl-4-nitro-, 1-oxide | HCID 95291 | — |
| Product | HCID 818140 | HCID 818140 | — |
Reaction Steps
To a solution of dimethylamine in tetrahydrofuran (2M, 20 ml) was added 2-methyl-4-nitropyridine N-oxide (3.08 g), and the mixture was stirred at 60° C. for 8 hours. The residue was evaporated under reduced pressure and purified by column chromatography (silica gel 75 g, 0 to 10% methanol in dichloromethane) to give 4-dimethylamino-2-methylpyridine N-oxide (1.76 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US06521643B1 |
|---|
| Source dataset | uspto-grants-2003_02 |
|---|
| ORD ID | ord-1ab8b8ce398b454fb70ac04085bbf341 |
|---|
| Source note | uspto-grants-2003_02 |
|---|
