HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 818140, compound → N,N,2-trimethylpyridin-4-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 818140 | HCID 818140 | — |
| Catalyst | Nickel | HCID 935 | — |
| Solvent | Isopropanol | HCID 3776 | — |
| Product | N,N,2-trimethylpyridin-4-amine | HCID 585150 | 90.3% |
Reaction Steps
A suspension of 4-dimethylamino-2-methylpyridine N-oxide (1.67 g) in 2-propanol (15 ml) was hydrogenated over Raney-nickel (50% suspension in water, 1 ml) under a hydrogen atmosphere for 3 hours. The catalyst was filtered off, and the filtrate was evaporated under reduced pressure to give 4-dimethylamino-2-methylpyridine (1.35 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06521643B1 |
| Source dataset | uspto-grants-2003_02 |
| ORD ID | ord-dc177305caf64e4f9802646abf70b1f1 |
| Source note | uspto-grants-2003_02 |