HuagongsheHuagongshe Chemistry Print Report · For research reference only
tert-butyl N-((3-(aminomethyl)phenyl)methyl)carbamate → N-(tert-butoxycarbonyl)-N'-[(5-isoquinolyl)sulfonyl]-1,3-xylylenediamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | tert-butyl N-((3-(aminomethyl)phenyl)methyl)carbamate | HCID 2756043 | — |
| Reactant | Isoquinoline-5-sulfonyl chloride hydrochloride | HCID 13116932 | — |
| Product | N-(tert-butoxycarbonyl)-N'-[(5-isoquinolyl)sulfonyl]-1,3-xylylenediamine | HCID 69525002 | 78.1% |
Reaction Steps
According to Reference Example 5, Step B, a reaction was performed by using isoquinoline-5-sulfonyl chloride hydrochloride (9 g) and Intermediate 62 (8 g) to obtain the title compound (11.3 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07094789B2 |
| Source dataset | uspto-grants-2006_08 |
| ORD ID | ord-5c0b777ddedc4173bf1e910f3e6f9fd8 |
| Source note | uspto-grants-2006_08 |