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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 106029Generated: October 31, 2026

Methyl 6-chloropyridine-3-carboxylate → 6-{3-Chloro-4-[2-(2-chloro-pyridin-4-yl)-3,3,3-trifluoro-2-hydroxy-1-methyl-propyl]-benzyloxy}-nicotinic acid methyl ester

https://huagongshe.com/reaction/106029

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 6-chloropyridine-3-carboxylateHCID 254249—
Reactant3-(2-Chloro-4-hydroxymethyl-phenyl)-2-(2-chloro-pyridin-4-yl)-1,1,1-trifluoro-butan-2-olHCID 25254449—
Product6-{3-Chloro-4-[2-(2-chloro-pyridin-4-yl)-3,3,3-trifluoro-2-hydroxy-1-methyl-propyl]-benzyloxy}-nicotinic acid methyl esterHCID 72310577—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (2/10)
ORD IDord-d4b038da3b2644269195821aae37839d
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (2/10)