HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Pyrrolidine → 4-Fluoro-N-(4-methoxy-7-pyrrolidin-1-yl-benzothiazol-2-yl)-benzamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Pyrrolidine | HCID 31268 | — |
| Edukt | 4-Bromo-2-nitroanisole | HCID 118533 | — |
| Edukt | 4-fluoro-N-(4-methoxy-7-morpholin-4-yl-benzothiazol-2-yl)-benzamide | HCID 10200214 | — |
| Produkt | 4-Fluoro-N-(4-methoxy-7-pyrrolidin-1-yl-benzothiazol-2-yl)-benzamide | HCID 22283185 | — |
Reaktionsschritte
The title compound was prepared strarting from 4-bromo-1-methoxy-2-nitro-benzene and pyrrolidine as described for 4-fluoro-N-(4-methoxy-7-morpholin-4-yl-benzothiazol-2-yl)-benzamide (Example 275) and obtained as a light brown solid in about 10% overall yield, MS: m/e=372 (M+H+).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06521754B2 |
| Quelldatensatz | uspto-grants-2003_02 |
| ORD ID | ord-644b2ec8d65140fa9ef505b98277d165 |
| Quellennotiz | uspto-grants-2003_02 |