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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1060739Generated: October 26, 2026

Bromine → Ethyl 2-bromoacetyl-4-methylpentanoate

https://huagongshe.com/reaction/1060739

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBromineHCID 24408—
ReactantPentanoic acid, 2-acetyl-4-methyl-, ethyl esterHCID 538758—
SolventChloroformHCID 6212—
ProductEthyl 2-bromoacetyl-4-methylpentanoateHCID 86585119—

Reaction Conditions

Temperature0 °C

Reaction Steps

A solution comprised of ethyl 2-acetyl-4-methylpentanoate (1.86 gm, 10 mmol) in chloroform (20 mL) was cooled to 0° C. and treated with bromine (0.6 mL, 11.0 mmol in 10 mL chloroform). The mixture was stirred for approximately 12 hours and then concentrated to provide ethyl 2-bromoacetyl-4-methylpentanoate as a crude product.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06525036B2
Source datasetuspto-grants-2003_02
ORD IDord-a3b7e3947a7a4c36b4a2c5c0ff9aa067
Source noteuspto-grants-2003_02