HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1060739Generated: October 26, 2026
Bromine → Ethyl 2-bromoacetyl-4-methylpentanoate
https://huagongshe.com/reaction/1060739
Participants
| Role | Name | HCID | Charge |
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| Reactant | Bromine | HCID 24408 | — |
| Reactant | Pentanoic acid, 2-acetyl-4-methyl-, ethyl ester | HCID 538758 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | Ethyl 2-bromoacetyl-4-methylpentanoate | HCID 86585119 | — |
Reaction Steps
A solution comprised of ethyl 2-acetyl-4-methylpentanoate (1.86 gm, 10 mmol) in chloroform (20 mL) was cooled to 0° C. and treated with bromine (0.6 mL, 11.0 mmol in 10 mL chloroform). The mixture was stirred for approximately 12 hours and then concentrated to provide ethyl 2-bromoacetyl-4-methylpentanoate as a crude product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US06525036B2 |
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| Source dataset | uspto-grants-2003_02 |
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| ORD ID | ord-a3b7e3947a7a4c36b4a2c5c0ff9aa067 |
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| Source note | uspto-grants-2003_02 |
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