Chloromethyl chlorosulfate → Chloromethyl 2-(2-(2-methoxyethoxy)-ethoxy)-ethoxy-acetate

HRID 1060783Notes

Reaction equation

HRID 1060783 reaction equation
[CH3:1][O:2][CH2:3][CH2:4][O:5][CH2:6][CH2:7][O:8][CH2:9][CH2:10][O:11][CH2:12][C:13]([OH:15])=[O:14].S(Cl)(O[CH2:20][Cl:21])(=O)=O>>[CH3:1][O:2][CH2:3][CH2:4][O:5][CH2:6][CH2:7][O:8][CH2:9][CH2:10][O:11][CH2:12][C:13]([O:15][CH2:20][Cl:21])=[O:14]

Participants

3

Reactant 2

HCID 2733556Chloromethyl chlorosulfateHCID 98593242,5,8,11-Tetraoxatridecan-13-oic acid

Product 1

HCID 19611287Chloromethyl 2-(2-(2-methoxyethoxy)-ethoxy)-ethoxy-acetate

Procedure

This compound was prepared from 2-(2-(2-methoxyethoxy)-ethoxy)-ethoxy-acetic acid and chloromethyl chlorosulfate as described in the general procedure given in Synthetic Communications 14, 857-864 (1984). The resulting oil was purified by distillation in vacuo, b.p.: 130-132° C. at 0.06 mbar.

Workup

  1. distillationThe resulting oil was purified by distillation in vacuo, b.p.: 130-132° C. at 0.06 mbar

Sources & evidence

ORD record
ord-939498f9f5fa4f8088b5cdd56e903fa1
Source dataset
uspto-grants-2003_02
Patent number
US06525077B2

Reaction notes

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