HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 6-fluoroimidazo[1,2-a]pyridine-2-carboxylate → 6-Fluoroimidazo[1,2-a]pyridine-2-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 6-fluoroimidazo[1,2-a]pyridine-2-carboxylate | HCID 40148106 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Product | 6-Fluoroimidazo[1,2-a]pyridine-2-carboxylic acid | HCID 22397508 | 99.4% |
Reaction Steps
A solution of 6-fluoro-imidazo[1,2-a]pyridine-2-carboxylic acid ethyl ester (1 g) in 4N HCl was refluxed for 4 hours. The solvent was evaporated to give the sub-title compound as a white solid (0.86 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06525070B2 |
| Source dataset | uspto-grants-2003_02 |
| ORD ID | ord-251936d88d474e4da44ae21b21de51b1 |
| Source note | uspto-grants-2003_02 |