HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 86758854, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 1,4-Dioxane | HCID 31275 | — |
| Reactant | HCID 18629424 | HCID 18629424 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 86758854 | HCID 86758854 | — |
Reaction Steps
N-[1-(4-cyano-3-fluoro-phenyl)-1-(3-pyridyl)-ethyl]-2-methylpropanesulfinamide (0.080 g, 0.232 mmol) was dissolved in MeOH (5 mL) and treated with 4M HCl solution in dioxane (0.58 mL, 2.32 mmol). The solution was stirred for 4 h, concentrated to dryness, and azeotroped with CH2Cl2 and Et2O to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06525074B2 |
| Source dataset | uspto-grants-2003_02 |
| ORD ID | ord-54252ce68eb24bacad2e62c126ef2ad8 |
| Source note | uspto-grants-2003_02 |