HRID1061004

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID13318871

4-(Diethylboranyl)pyridine

C9H14BN

结构：CC(C)(C)OC(=O)c1cc(Br)ccc1C(=O)N1CCN(S(=O)(=O)c2ccc3cc(Cl)ccc3c2)CC1

HCID22709864

未命名化合物

PRODUCTS

生成物

结构：CC(C)(C)OC(=O)c1cc(-c2ccncc2)ccc1C(=O)N1CCN(S(=O)(=O)c2ccc3cc(Cl)ccc3c2)CC1.Cl

HCID22710746

未命名化合物

PROCEDURE

实验过程

In a similar manner to Referential Example 7 except for the use of 1-[4-bromo-2-(tert-butoxycarbonyl)benzoyl]-4-[(6-chloronaphthalen-2-yl)sulfonyl]piperazine and diethyl(4-pyridyl)borane as the raw materials, the reaction was conducted, whereby the title compound was obtained.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-31417add813c4a56a6eb35184e0572fd
来源数据集: uspto-grants-2003_02
DOI: 10.6084/m9.figshare.5104873.v1
专利: US06525042B1
来源说明: uspto-grants-2003_02

反应 SMILES

Br[C:2]1[CH:29]=[CH:28][C:5]([C:6]([N:8]2[CH2:13][CH2:12][N:11]([S:14]([C:17]3[CH:26]=[CH:25][C:24]4[C:19](=[CH:20][CH:21]=[C:22]([Cl:27])[CH:23]=4)[CH:18]=3)(=[O:16])=[O:15])[CH2:10][CH2:9]2)=[O:7])=[C:4]([C:30]([O:32][C:33]([CH3:36])([CH3:35])[CH3:34])=[O:31])[CH:3]=1.C(B(CC)[C:40]1[CH:45]=[CH:44][N:43]=[CH:42][CH:41]=1)C>>[ClH:27].[C:33]([O:32][C:30]([C:4]1[CH:3]=[C:2]([C:40]2[CH:45]=[CH:44][N:43]=[CH:42][CH:41]=2)[CH:29]=[CH:28][C:5]=1[C:6]([N:8]1[CH2:9][CH2:10][N:11]([S:14]([C:17]2[CH:26]=[CH:25][C:24]3[C:19](=[CH:20][CH:21]=[C:22]([Cl:27])[CH:23]=3)[CH:18]=2)(=[O:16])=[O:15])[CH2:12][CH2:13]1)=[O:7])=[O:31])([CH3:36])([CH3:34])[CH3:35]