HRID1061017

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：Cl.O=S(=O)(c1ccc2cc(Cl)ccc2c1)N1CCNCC1

HCID22709766

未命名化合物

结构：COC(=O)c1ccc2c(c1)CCC(CNC(=O)OC(C)(C)C)C2

HCID22709912

未命名化合物

PRODUCTS

生成物

结构：CC(C)(C)OC(=O)NCC1CCc2cc(C(=O)N3CCN(S(=O)(=O)c4ccc5cc(Cl)ccc5c4)CC3)ccc2C1

HCID22710919

未命名化合物

PROCEDURE

实验过程

In a similar manner to Referential Example 48 except for the use of (2RS)-2-(N-tert-butoxycarbonylaminomethyl)-6-methoxycarbonyl-1,2,3,4-tetrahydronaphthalene and 1-[(6-chloronaphthalen-2-yl)sulfonyl]piperazine hydrochloride, the reaction was conducted, whereby the title compound was obtained.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-9bca2da8c2604eaeb0251227188d610a
来源数据集: uspto-grants-2003_02
DOI: 10.6084/m9.figshare.5104873.v1
专利: US06525042B1
来源说明: uspto-grants-2003_02

反应 SMILES

[C:1]([O:5][C:6]([NH:8][CH2:9][CH:10]1[CH2:19][CH2:18][C:17]2[C:12](=[CH:13][CH:14]=[C:15]([C:20](OC)=[O:21])[CH:16]=2)[CH2:11]1)=[O:7])([CH3:4])([CH3:3])[CH3:2].Cl.[Cl:25][C:26]1[CH:27]=[C:28]2[C:33](=[CH:34][CH:35]=1)[CH:32]=[C:31]([S:36]([N:39]1[CH2:44][CH2:43][NH:42][CH2:41][CH2:40]1)(=[O:38])=[O:37])[CH:30]=[CH:29]2>>[C:1]([O:5][C:6]([NH:8][CH2:9][CH:10]1[CH2:19][CH2:18][C:17]2[CH:16]=[C:15]([C:20]([N:42]3[CH2:41][CH2:40][N:39]([S:36]([C:31]4[CH:30]=[CH:29][C:28]5[C:33](=[CH:34][CH:35]=[C:26]([Cl:25])[CH:27]=5)[CH:32]=4)(=[O:37])=[O:38])[CH2:44][CH2:43]3)=[O:21])[CH:14]=[CH:13][C:12]=2[CH2:11]1)=[O:7])([CH3:4])([CH3:2])[CH3:3]