HRID1061021

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：Cl.O=S(=O)(c1ccc2cc(Cl)ccc2c1)N1CCNCC1

HCID22709766

未命名化合物

结构：CC(C)(C)OC(=O)N1CC[C@H](Oc2ccc(C(=O)O)cc2)C1

HCID58893878

未命名化合物

PRODUCTS

生成物

结构：CC(C)(C)OC(=O)N1CC[C@H](Oc2ccc(C(=O)N3CCN(S(=O)(=O)c4ccc5cc(Cl)ccc5c4)CC3)cc2)C1

HCID69700796

未命名化合物

PROCEDURE

实验过程

In a similar manner to Referential Example 12 except for the use of 4-[[(3S)-1-tert-butoxycarbonyl-3-pyrrolidinyl]oxy]benzoic acid and 1-[(6-chloronaphthalen-2-yl)sulfonyl]piperazine hydrochloride as the raw materials, the reaction was conducted, whereby the title compound was obtained.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-34884e10378f458c847fb00c5b7c9a09
来源数据集: uspto-grants-2003_02
DOI: 10.6084/m9.figshare.5104873.v1
专利: US06525042B1
来源说明: uspto-grants-2003_02

反应 SMILES

[C:1]([O:5][C:6]([N:8]1[CH2:12][CH2:11][C@H:10]([O:13][C:14]2[CH:22]=[CH:21][C:17]([C:18]([OH:20])=O)=[CH:16][CH:15]=2)[CH2:9]1)=[O:7])([CH3:4])([CH3:3])[CH3:2].Cl.[Cl:24][C:25]1[CH:26]=[C:27]2[C:32](=[CH:33][CH:34]=1)[CH:31]=[C:30]([S:35]([N:38]1[CH2:43][CH2:42][NH:41][CH2:40][CH2:39]1)(=[O:37])=[O:36])[CH:29]=[CH:28]2>>[C:1]([O:5][C:6]([N:8]1[CH2:12][CH2:11][C@H:10]([O:13][C:14]2[CH:22]=[CH:21][C:17]([C:18]([N:41]3[CH2:40][CH2:39][N:38]([S:35]([C:30]4[CH:29]=[CH:28][C:27]5[C:32](=[CH:33][CH:34]=[C:25]([Cl:24])[CH:26]=5)[CH:31]=4)(=[O:37])=[O:36])[CH2:43][CH2:42]3)=[O:20])=[CH:16][CH:15]=2)[CH2:9]1)=[O:7])([CH3:3])([CH3:4])[CH3:2]