HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(6-Chloronaphth-2-ylsulphonyl)piperazine hydrochloride → 1-[4-[[(3S)-1-tert-Butoxycarbonylpyrrolidin-3-yl]oxy]benzoyl]-4-[(6-chloronaphthalen-2-yl)sulfonyl]piperazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(6-Chloronaphth-2-ylsulphonyl)piperazine hydrochloride | HCID 22709766 | — |
| Reactant | 4-[[(3S)-1-tert-butoxycarbonyl3-pyrrolidinyl]oxy]benzoic acid | HCID 58893878 | — |
| Product | 1-[4-[[(3S)-1-tert-Butoxycarbonylpyrrolidin-3-yl]oxy]benzoyl]-4-[(6-chloronaphthalen-2-yl)sulfonyl]piperazine | HCID 69700796 | — |
Reaction Steps
In a similar manner to Referential Example 12 except for the use of 4-[[(3S)-1-tert-butoxycarbonyl-3-pyrrolidinyl]oxy]benzoic acid and 1-[(6-chloronaphthalen-2-yl)sulfonyl]piperazine hydrochloride as the raw materials, the reaction was conducted, whereby the title compound was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06525042B1 |
| Source dataset | uspto-grants-2003_02 |
| ORD ID | ord-34884e10378f458c847fb00c5b7c9a09 |
| Source note | uspto-grants-2003_02 |