Sodium Hydroxide → Sodium thiazolo[5,4-c]pyridine-2-carboxylate

HRID 1061027Notes

Reaction equation

HRID 1061027 reaction equation
[N:1]1[C:9]2[CH:8]=[CH:7][N:6]=[CH:5][C:4]=2[S:3][C:2]=1[C:10]([O:12]CC)=[O:11].[OH-].[Na+:16]>O1CCCC1>[N:1]1[C:9]2[CH:8]=[CH:7][N:6]=[CH:5][C:4]=2[S:3][C:2]=1[C:10]([O-:12])=[O:11].[Na+:16]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 14252940Ethyl thiazolo[5,4-c]pyridine-2-carboxylate

Product 1

HCID 23694146Sodium thiazolo[5,4-c]pyridine-2-carboxylate

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

In tetrahydrofuran (12 ml), ethyl thiazolo[5,4-c]pyridine-2-carboxylate (0.61 g) was dissolved, followed by the addition of a 1N aqueous sodium hydroxide solution (3 ml). After stirring at room temperature for 30 minutes, the insoluble matter was filtered off. Without purification, the filtrate was provided for the subsequent reaction.

Workup

  1. filtrationthe insoluble matter was filtered off
  2. customWithout purification
  3. customthe filtrate was provided for the subsequent reaction

Sources & evidence

ORD record
ord-8aa21e316eea4cd9aabcda7bf76a0ac6
Source dataset
uspto-grants-2003_02
Patent number
US06525042B1

Reaction notes

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