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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1061060Generated: November 4, 2026

4-(2-Amino-1,3-thiazol-4-yl)benzoic acid → 1-[4-(2-Aminothiazol-4-yl)benzoyl]-4-[(6-chloronaphthalen-2-yl)sulfonyl]piperazine hydrochloride

https://huagongshe.com/reaction/1061060

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(2-Amino-1,3-thiazol-4-yl)benzoic acidHCID 613179—
Reactant1-(6-Chloronaphth-2-ylsulphonyl)piperazine hydrochlorideHCID 22709766—
Product1-[4-(2-Aminothiazol-4-yl)benzoyl]-4-[(6-chloronaphthalen-2-yl)sulfonyl]piperazine hydrochlorideHCID 22710110—

Reaction Steps

In a similar manner to Example 4 except for the use of 4-(2-aminothiazol-4-yl)benzoic acid and 1-[(6-chloronaphthalen-2-yl)sulfonyl]piperazine hydrochloride as the raw materials, the reaction was conducted, whereby the title compound was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06525042B1
Source datasetuspto-grants-2003_02
ORD IDord-7dd208d474764bc08be8ff66d672a29a
Source noteuspto-grants-2003_02