HRID1061081

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：COC(=O)CC1CN(S(=O)(=O)c2ccc3cc(Cl)ccc3c2)CCN1

HCID22709489

未命名化合物

HCID68499643

未命名化合物

PRODUCTS

生成物

结构：COC(=O)CC1CN(S(=O)(=O)c2ccc3cc(Cl)ccc3c2)CCN1C(=O)c1ccc(-c2ccccn2)cc1

HCID18628922

未命名化合物

PROCEDURE

实验过程

In a similar manner to Referential Example 116 except for the use of 1-[(6-chloronaphthalen-2-yl)sulfonyl]-3-methoxycarbonylmethylpiperazine and 4-(2-pyridyl)benzoic acid hydrochloride as the raw materials, the reaction was conducted, whereby the title compound was obtained.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-1e36394f471c43a0a466dbc8789d52e9
来源数据集: uspto-grants-2003_02
DOI: 10.6084/m9.figshare.5104873.v1
专利: US06525042B1
来源说明: uspto-grants-2003_02

反应 SMILES

[Cl:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[CH:8]=[C:7]([S:12]([N:15]1[CH2:20][CH2:19][NH:18][CH:17]([CH2:21][C:22]([O:24][CH3:25])=[O:23])[CH2:16]1)(=[O:14])=[O:13])[CH:6]=[CH:5]2.Cl.[N:27]1[CH:32]=[CH:31][CH:30]=[CH:29][C:28]=1[C:33]1[CH:41]=[CH:40][C:36]([C:37](O)=[O:38])=[CH:35][CH:34]=1>>[Cl:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[CH:8]=[C:7]([S:12]([N:15]1[CH2:20][CH2:19][N:18]([C:37](=[O:38])[C:36]3[CH:40]=[CH:41][C:33]([C:28]4[CH:29]=[CH:30][CH:31]=[CH:32][N:27]=4)=[CH:34][CH:35]=3)[CH:17]([CH2:21][C:22]([O:24][CH3:25])=[O:23])[CH2:16]1)(=[O:13])=[O:14])[CH:6]=[CH:5]2