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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1061081Generated: October 25, 2026

1-[(6-Chloronaphthalen-2-yl)sulfonyl]-3-methoxycarbonylmethylpiperazine → 4-[(6-Chloronaphthalen-2-yl)sulfonyl]-2-methoxycarbonylmethyl-1-[4-(pyridin-2-yl)benzoyl]piperazine

https://huagongshe.com/reaction/1061081

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-[(6-Chloronaphthalen-2-yl)sulfonyl]-3-methoxycarbonylmethylpiperazineHCID 22709489—
Reactant4-(2-Pyridyl)benzoic acid hydrochlorideHCID 68499643—
Product4-[(6-Chloronaphthalen-2-yl)sulfonyl]-2-methoxycarbonylmethyl-1-[4-(pyridin-2-yl)benzoyl]piperazineHCID 18628922—

Reaction Steps

In a similar manner to Referential Example 116 except for the use of 1-[(6-chloronaphthalen-2-yl)sulfonyl]-3-methoxycarbonylmethylpiperazine and 4-(2-pyridyl)benzoic acid hydrochloride as the raw materials, the reaction was conducted, whereby the title compound was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06525042B1
Source datasetuspto-grants-2003_02
ORD IDord-1e36394f471c43a0a466dbc8789d52e9
Source noteuspto-grants-2003_02