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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1061409Generated: November 2, 2026

Norfenefrine → HCID 22220486, compound

https://huagongshe.com/reaction/1061409

Reaction equation

Participants

RoleNameHCIDCharge
ReactantNorfenefrineHCID 4538—
Reactant4-{[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}benzene-1-sulfonyl chlorideHCID 2783039—
Reactant1-(4-Amino-phenyl)-piperidin-4-one hydrochlorideHCID 22220240—
ProductHCID 22220486HCID 22220486—

Reaction Steps

The title compound was prepared from 1-(4-aminophenyl)-4-piperidone hydrochloride (which was obtained in Example 224), 4-(3-chloro-5-trifluoromethyl-2-pyridyloxy)benzenesulfonyl chloride, and DL-norphenylephrine according to the procedure of Example 346; MS (ES) m/z: 663.2 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06525202B2
Source datasetuspto-grants-2003_02
ORD IDord-d1c66cfe334d4363b9ef08d04997fc2a
Source noteuspto-grants-2003_02