Ethanesulfonylchloride, 2-chloro- → HCID 22058069, compound

HRID 1061493Notes

Reaction equation

[Cl:1][CH2:2][CH2:3][CH2:4][S:5](Cl)(=[O:7])=[O:6].Cl[CH2:10][CH2:11]S(Cl)(=O)=O.[CH3:16][CH:17]1[CH2:22][CH2:21][NH:20][CH2:19][CH2:18]1.[CH3:23][CH:24]1[CH2:29][CH2:28][CH2:27][NH:26][CH2:25]1>>[ClH:1].[CH3:16][CH:17]1[CH2:22][CH2:21][N:20]([CH2:2][CH2:3][CH2:4][S:5]([N:26]2[C:25]3[C:29](=[CH:10][CH:11]=[CH:23][CH:24]=3)[CH2:28][CH2:27]2)(=[O:7])=[O:6])[CH2:19][CH2:18]1

Participants

Reactant 4

HCID 15385Ethanesulfonylchloride, 2-chloro-

HCID 154103-Chloropropanesulphonyl chloride

HCID 693814-Methylpiperidine

HCID 790813-Methylpiperidine

Product 1

HCID 22058069HCID 22058069, compound

Procedure

By following the procedures of Example 2, but replacing the 3-chloropropanesulfonyl chloride in Step 1 with 2-chloroethanesulfonyl chloride and the 4-methylpiperidine in Step 2 with 3-methylpiperidine, the following compound was prepared. The 1H NMR spectrum and the mass spectrum for this compound were consistent with the assigned structure.

Sources & evidence

ORD record: ord-044f4d645cfc4d0692a7d3f7ee149b08
Source dataset: uspto-grants-2005_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06960579B1

Reaction notes

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