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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1061497Generated: October 25, 2026

3,5-Dichloro-2,4,6-trifluoropyridine → 4-Pyridinamine, 3,5-dichloro-2,6-difluoro-

https://huagongshe.com/reaction/1061497

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3,5-Dichloro-2,4,6-trifluoropyridineHCID 61273—
Reactant4-Amino-3-chloro-2,5,6-trifluoro-pyridineHCID 3488144—
Product4-Pyridinamine, 3,5-dichloro-2,6-difluoro-HCID 76089—

Reaction Steps

This compound was prepared from 3,5-dichloro-2,4,6-trifluoropyridine (24.5 g) by a procedure similar to that described for compound 2: yield, 23.7 g (98%); mp 110° C. (Lit., Chambers et al., J. Chem. Soc. 1964, 5634-5640 mp 112-113° C.).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06960568B2
Source datasetuspto-grants-2005_11
ORD IDord-3c492f8194474dd3a0abf35b748976b2
Source noteuspto-grants-2005_11