HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 22229205, compound → HCID 22285081, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 22229205 | HCID 22229205 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 22285081 | HCID 22285081 | 100.6% |
Reaction Steps
41.7 g (86.4 mmol) of benzyl 4-[4-(tert-butyloxycarbonylaminomethyl)benzylaminocarbonyl]piperazine-1-carboxylate (starting material A11 ) in 1.0 l of methanol are hydrogenated over palladium/carbon (5%) for 4 h. The catalyst is filtered off and the solvent is removed, giving 30.3 g of the title compound as a colorless oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06960588B1 |
| Source dataset | uspto-grants-2005_11 |
| ORD ID | ord-6127ea637c3046768bd0af53d479d8be |
| Source note | uspto-grants-2005_11 |