Benzoic Acid → 2-Amino-5-bromobenzophenone

HRID 1061864Notes

Reaction equation

HRID 1061864 reaction equation
[C:1]([OH:9])(=O)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[Br:10][C:11]1[CH:17]=[CH:16][C:14]([NH2:15])=[CH:13][CH:12]=1>>[NH2:15][C:14]1[CH:16]=[CH:17][C:11]([Br:10])=[CH:12][C:13]=1[C:1]([C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1)=[O:9]

Participants

3

Reactant 2

HCID 243Benzoic AcidHCID 78074-Bromoaniline

Product 1

HCID 996772-Amino-5-bromobenzophenoneYield 19.8%

Procedure

The procedure was in the same manner as described in example 15, except that the starting material was benzoic acid instead of p-chlorobenzoic acid and 4-bromoaniline instead of 4-chloroaniline. The title compound was obtained as yellow needle crystal, and yield 19.8%, m.p.109-110° C.

Sources & evidence

ORD record
ord-2c535ab9358a45d38e9c976d4d01f759
Source dataset
uspto-grants-2005_11
Patent number
US06960611B2

Reaction notes

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