HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclopropylamine → HCID 178450029, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclopropylamine | HCID 69828 | — |
| Reactant | Methyl 1-bromomethyl-6-[1-hydroxy-2-methyl-1-(1-trityl-1H-imidazol-4-yl)propyl]-2-naphthoate | HCID 22285061 | — |
| Product | HCID 178450029 | HCID 178450029 | — |
Reaction Steps
By a ring closure reaction, a detritylation reaction and purification in the same manner as in Example 1 using methyl 1-bromomethyl-6-[1-hydroxy-2-methyl-1-(1-trityl-1H-imidazol-4-yl)propyl]-2-naphthoate (1.32 g) and cyclopropylamine (3.0 ml), the title compound (0.58 g) was obtained as a colorless amorphous solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06960586B2 |
| Source dataset | uspto-grants-2005_11 |
| ORD ID | ord-257444ca33ea41e8ae9a54413453c9cb |
| Source note | uspto-grants-2005_11 |