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HRID1061888

反应详情

EQUATION

反应方程式

HRID 1061888 的结构方程式

REACTANTS

反应物

2
结构：NCC(F)(F)F
HCID9773

Ethanamine, 2,2,2-trifluoro-

C2H4F3N

结构：COC(=O)c1ccc2cc(C(O)(c3cn(C(c4ccccc4)(c4ccccc4)c4ccccc4)cn3)C(C)C)ccc2c1CBr
HCID22285061

未命名化合物

PRODUCTS

生成物

1
结构：CC(C)C(O)(c1ccc2c3c(ccc2c1)C(=O)N(CC(F)(F)F)C3)c1c[nH]cn1
HCID178450031

未命名化合物

PROCEDURE

实验过程

By a ring closure reaction, a detritylation reaction and purification in the same manner as in Example 1 using methyl 1-bromomethyl-6-[1-hydroxy-2-methyl-1-(1-trityl-1H-imidazol-4-yl)propyl]-2-naphthoate (0.66 g) and 2,2,2-trifluoroethylamine (2.0 ml), the title compound (0.34 g) was obtained as a colorless amorphous solid.

WORKUP

后处理

  1. customBy a ring closure reaction