Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ethanamine, 2,2,2-trifluoro- → HCID 178450031, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ethanamine, 2,2,2-trifluoro- | HCID 9773 | — |
| 반응물 | Methyl 1-bromomethyl-6-[1-hydroxy-2-methyl-1-(1-trityl-1H-imidazol-4-yl)propyl]-2-naphthoate | HCID 22285061 | — |
| 생성물 | HCID 178450031 | HCID 178450031 | — |
반응 단계
By a ring closure reaction, a detritylation reaction and purification in the same manner as in Example 1 using methyl 1-bromomethyl-6-[1-hydroxy-2-methyl-1-(1-trityl-1H-imidazol-4-yl)propyl]-2-naphthoate (0.66 g) and 2,2,2-trifluoroethylamine (2.0 ml), the title compound (0.34 g) was obtained as a colorless amorphous solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06960586B2 |
| 출처 데이터셋 | uspto-grants-2005_11 |
| ORD ID | ord-120db2486d1d428fa368800fbfacb67c |
| 출처 메모 | uspto-grants-2005_11 |