(4-Methoxyphenyl)boronic acid → (4'-Methoxy-3-nitro-biphenyl-4-yl)-carbamic acid tert.-butyl ester

HRID 1061902Notes

Reaction equation

HRID 1061902 reaction equation
[C:1]([O:5][C:6](=[O:18])[NH:7][C:8]1[CH:13]=[CH:12][C:11](I)=[CH:10][C:9]=1[N+:15]([O-:17])=[O:16])([CH3:4])([CH3:3])[CH3:2].[CH3:19][O:20][C:21]1[CH:26]=[CH:25][C:24](B(O)O)=[CH:23][CH:22]=1>>[C:1]([O:5][C:6](=[O:18])[NH:7][C:8]1[CH:13]=[CH:12][C:11]([C:24]2[CH:25]=[CH:26][C:21]([O:20][CH3:19])=[CH:22][CH:23]=2)=[CH:10][C:9]=1[N+:15]([O-:17])=[O:16])([CH3:4])([CH3:3])[CH3:2]

Participants

3

Reactant 2

HCID 201262(4-Methoxyphenyl)boronic acidHCID 23554339Tert-butyl (4-iodo-2-nitrophenyl)carbamate

Product 1

HCID 69592776(4'-Methoxy-3-nitro-biphenyl-4-yl)-carbamic acid tert.-butyl ester

Procedure

Prepared from (4-iodo-2-nitro-phenyl)-carbamic acid tert.-butyl ester (Example A1) and 4-methoxyphenylboronic acid according to the general procedure B. Obtained as a yellow solid (637 mg).

Sources & evidence

ORD record
ord-7ae47580bcb94a28abade1996d21115d
Source dataset
uspto-grants-2005_11
Patent number
US06960578B2

Reaction notes

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