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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1062001Generated: October 26, 2026

Methyl 3-(1H-1,2,4-triazol-1-YL)benzoate → 3-Oxo-3-(3-[1,2,4]triazol-1-yl-phenyl)-propionic acid tert-butyl ester

https://huagongshe.com/reaction/1062001

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 3-(1H-1,2,4-triazol-1-YL)benzoateHCID 22224836—
ReactantLithium Tert-butyl AcetateHCID 86586795—
Product3-Oxo-3-(3-[1,2,4]triazol-1-yl-phenyl)-propionic acid tert-butyl esterHCID 69592807—

Reaction Steps

Prepared from methyl 3-[1,2,4]triazol-1-yl-benzoate [CAS-No. 167626-27-9] by treatment with lithium tert.-butyl acetate according to general procedure H (method b). Obtained as an orange liquid (2.41 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06960578B2
Source datasetuspto-grants-2005_11
ORD IDord-d27e807de93d43e0a371ce8c8c22b9f5
Source noteuspto-grants-2005_11