huagongshe.com
HRID1062028

反应详情

EQUATION

反应方程式

HRID 1062028 的结构方程式

REACTANTS

反应物

3
结构：O=C(OC(=O)C(F)(F)F)C(F)(F)F
HCID9845

Trifluoroacetic anhydride

C4F6O3

结构：COC(=O)c1cccc(-n2cncn2)c1
HCID22224836

Methyl 3-(1H-1,2,4-triazol-1-yl)benzoate

C10H9N3O2

结构：CC(=O)OC(C)(C)C.[Li]
HCID86586795

未命名化合物

PRODUCTS

生成物

1
结构：CC(C)(C)OC(=O)CC(=O)c1cccc(-n2cncn2)c1
HCID69592807

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CC(C)=O.O=C(O)C(F)(F)F
溶剂HCID86586799

未命名化合物

PROCEDURE

实验过程

The 3-oxo-3-(3-[1,2,4]triazol-1-yl-phenyl)-propionic acid tert.-butyl ester was prepared from 3-[1,2,4]triazol-1-yl-benzoic acid methyl ester [CAS-No. 167626-27-9] by treatment with lithium tert.-butyl acetate according to general procedure H (method b). Prepared from (Example H6) by stirring in TFA/acetone with TFAA according to general procedure J (method b). Obtained as a yellow solid (539 mg).