HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,4-Dioxane-2,6-dione → HCID 22286965, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,4-Dioxane-2,6-dione | HCID 78232 | — |
| Reactant | 4-Amino-1-methyl-3-propyl-1H-pyrazole-5-carboxamide | HCID 3338044 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 22286965 | HCID 22286965 | — |
Reaction Steps
1.1 13.5 g of diglycolic anhydride are added at 15° to a solution of 20.5 g of 1-methyl-3-propyl4-amino-5-aminocarbonyl-1H-pyrazole (“Z6”) in 400 ml of dichloromethane, and the mixture is stirred for a further 1 hour. The mixture is subjected to conventional work-up, giving 32.5 g of [(5-aminocarbonyl-1-methyl-3-propyl-1H-pyrazol4-ylcarbamoyl)methoxy]-acetic acid (“Z7”).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06960661B2 |
| Source dataset | uspto-grants-2005_11 |
| ORD ID | ord-f06a7813e4d24c469ce98386330f78a3 |
| Source note | uspto-grants-2005_11 |