反应详情

Into a 200 ml reactor thoroughly dried and purged with nitrogen, 34.15 g (316.0 mmol) of paracresol, 2.50 g of Umberist-15E (trade name, available from Organo Co.) and 20 ml of toluene were introduced. To the reactor, a solution containing 14.40 g (105.0 mmol) of 4-cumylphenol diluted with 30 ml of a toluene was dropwise added at 80° C., followed by stirring for 17 hours. After the system was cooled to room temperature, the reaction solution was filtered with washing with hexane. The resulting liquid was purified by silica gel column chromatography to obtain 10.52 g (yield: 44%) of 2-cumyl-4-methylphenol.

1. customInto a 200 ml reactor thoroughly dried
2. additionwere introduced
3. additionwas dropwise added at 80° C.
4. filtrationthe reaction solution was filtered
5. washwith washing with hexane
6. customThe resulting liquid was purified by silica gel column chromatography