反应详情

Compound (21) (0.00227 mol) was stirred in ethylacetate (50 ml). The mixture was washed with NaHCO3 (50 ml saturated solution), then washed with brine, dried, filtered and the solvent was evaporated. The residue was crystallized from methanol, filtered off and dried, yielding 0.60 g (70.6%) of 4-[[4-[(2,6-dichlorophenyl)methyl]-6-(hydroxyamino)-1,3,5-triazin-2-yl]amino]benzonitrile (compound 33).

1. washThe mixture was washed with NaHCO3 (50 ml saturated solution)
2. washwashed with brine
3. customdried
4. filtrationfiltered
5. customthe solvent was evaporated
6. customThe residue was crystallized from methanol
7. filtrationfiltered off
8. customdried