HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Bromine → 4-Methoxy-7-morpholinobenzo[d]thiazol-2-amine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Bromine | HCID 24408 | — |
| Edukt | 1-(2-Methoxy-5-morpholinophenyl)thiourea | HCID 22015733 | — |
| Lösungsmittel | Chloroform | HCID 6212 | — |
| Produkt | 4-Methoxy-7-morpholinobenzo[d]thiazol-2-amine | HCID 11402861 | — |
Reaktionsschritte
(2-Methoxy-5-morpholin-4-yl-phenyl)-thiourea (5.0 g, 19 mmol) in chloroform (130 ml) are treated with bromine (960 □1) and the mixture refluxed for 18 hours. After removal of the volatile components in vacuo, the product is recrystallized from THF (2.8 g, 57%). MS: m/e=266 (M+).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06963000B2 |
| Quelldatensatz | uspto-grants-2005_11 |
| ORD ID | ord-a63174d147e74b7983c2d9c9b3cd9398 |
| Quellennotiz | uspto-grants-2005_11 |