Dimethylamine → 7-Chloro-N,N-dimethylthieno[3,2-b]pyridine-2-carboxamide

HRID 1063138Notes

Reaction equation

[CH3:1][NH:2][CH3:3].[Cl:4][C:5]1[CH:10]=[CH:9][N:8]=[C:7]2[CH:11]=[C:12]([C:14]([O-:16])=O)[S:13][C:6]=12.[Li+]>>[CH3:1][N:2]([CH3:3])[C:14]([C:12]1[S:13][C:6]2[C:7](=[N:8][CH:9]=[CH:10][C:5]=2[Cl:4])[CH:11]=1)=[O:16]

Participants

Reactant 2

HCID 674Dimethylamine

HCID 23677819Lithium 7-chlorothieno[3,2-b]pyridine-2-carboxylate

Product 1

HCID 221435377-Chloro-N,N-dimethylthieno[3,2-b]pyridine-2-carboxamide

Procedure

The title compound was prepared from dimethyl amine and lithium 7-chloro-thieno[3,2-b]pyridine-2-carboxylate by a procedure analogous to Example 1B. MS: 239/241 (MH+); HPLC Rf: n.d.; HPLC purity: n.d.

Sources & evidence

ORD record: ord-495da16d536343cfb5a01b72782af5d0
Source dataset: uspto-grants-2005_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06964961B2

Reaction notes

Loading…