5-Amino-2-methylindole → HCID 69737370, compound

HRID 1063139Notes

Reaction equation

HRID 1063139 reaction equation
[CH3:1][C:2]1[NH:3][C:4]2[C:9]([CH:10]=1)=[CH:8][C:7]([NH2:11])=[CH:6][CH:5]=2.[CH3:12][N:13]([CH3:26])[C:14]([C:16]1[S:24][C:23]2[C:18](=[N:19][CH:20]=[CH:21][C:22]=2Cl)[CH:17]=1)=[O:15]>>[CH3:12][N:13]([CH3:26])[C:14]([C:16]1[S:24][C:23]2[C:18](=[N:19][CH:20]=[CH:21][C:22]=2[NH:11][C:7]2[CH:8]=[C:9]3[C:4](=[CH:5][CH:6]=2)[NH:3][C:2]([CH3:1])=[CH:10]3)[CH:17]=1)=[O:15]

Participants

3

Reactant 2

HCID 27339925-Amino-2-methylindoleHCID 221435377-Chloro-N,N-dimethylthieno[3,2-b]pyridine-2-carboxamide

Product 1

HCID 69737370HCID 69737370, compound

Procedure

The title compound was prepared from 2-methyl-1H-indol-5-ylamine and 7-chloro-thieno[3,2-b]pyridine-2-carboxylic acid dimethylamide by a procedure analogous to Example 1C. MS: 351 (MH+); HPLC Rf: 3.87 min.; HPLC purity: 94%.

Sources & evidence

ORD record
ord-49fee27922634c6e93e6cc442a0ffd34
Source dataset
uspto-grants-2005_11
Patent number
US06964961B2

Reaction notes

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