N-(3-Aminopropyl)morpholine → HCID 91224766, compound

HRID 1063150Notes

Reaction equation

HRID 1063150 reaction equation
[N:1]1([CH2:7][CH2:8][CH2:9][NH2:10])[CH2:6][CH2:5][O:4][CH2:3][CH2:2]1.[Cl:11][C:12]1[CH:17]=[CH:16][N:15]=[C:14]2[CH:18]=[C:19]([C:21]([O-])=[O:22])[S:20][C:13]=12.[Li+]>>[N:1]1([CH2:7][CH2:8][CH2:9][NH:10][C:21]([C:19]2[S:20][C:13]3[C:14](=[N:15][CH:16]=[CH:17][C:12]=3[Cl:11])[CH:18]=2)=[O:22])[CH2:6][CH2:5][O:4][CH2:3][CH2:2]1

Participants

3

Reactant 2

HCID 61055N-(3-Aminopropyl)morpholineHCID 23677819Lithium 7-chlorothieno[3,2-b]pyridine-2-carboxylate

Product 1

HCID 91224766HCID 91224766, compound

Procedure

The title compound was prepared from 3-morpholin-4-ylpropylamine and lithium 7-chloro-thieno[3,2-b]pyridine-2-carboxylate by a procedure analogous to Example 1B. MS: 340/342 (MH+); HPLC Rf: 3.45 min.; HPLC purity: 89%.

Sources & evidence

ORD record
ord-16158305c7de49ed8bc6fbbab4793a4e
Source dataset
uspto-grants-2005_11
Patent number
US06964961B2

Reaction notes

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