5-Amino-2-methylindole → HCID 69737239, compound

HRID 1063165Notes

Reaction equation

HRID 1063165 reaction equation
[CH3:1][C:2]1[NH:3][C:4]2[C:9]([CH:10]=1)=[CH:8][C:7]([NH2:11])=[CH:6][CH:5]=2.[N:12]1[CH:17]=[CH:16][CH:15]=[C:14]([NH:18][C:19]([C:21]2[S:29][C:28]3[C:23](=[N:24][CH:25]=[CH:26][C:27]=3Cl)[CH:22]=2)=[O:20])[CH:13]=1>>[N:12]1[CH:17]=[CH:16][CH:15]=[C:14]([NH:18][C:19]([C:21]2[S:29][C:28]3[C:23](=[N:24][CH:25]=[CH:26][C:27]=3[NH:11][C:7]3[CH:8]=[C:9]4[C:4](=[CH:5][CH:6]=3)[NH:3][C:2]([CH3:1])=[CH:10]4)[CH:22]=2)=[O:20])[CH:13]=1

Participants

3

Reactant 2

HCID 27339925-Amino-2-methylindoleHCID 69735730HCID 69735730, compound

Product 1

HCID 69737239HCID 69737239, compound

Procedure

The title compound was prepared from 2-methyl-1H-indol-5-ylamine and 7-chloro-thieno[3,2-b]pyridine-2-carboxylic acid pyridin-3-ylamide by a procedure analogous to Example 1C. MS: 400 (MH+), HPLC Rf: 4.58 min.; HPLC purity 99%.

Sources & evidence

ORD record
ord-8e93bf3acf36402eba7e1257c9135c41
Source dataset
uspto-grants-2005_11
Patent number
US06964961B2

Reaction notes

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