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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1063165Generated: November 1, 2026

5-Amino-2-methylindole → 7-(2-Methyl-1h-indol-5-ylamino)-thieno[3,2-b]pyridine-2-carboxylic acid pyridin-3-ylamide

https://huagongshe.com/reaction/1063165

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Amino-2-methylindoleHCID 2733992—
ReactantHCID 69735730HCID 69735730—
Product7-(2-Methyl-1h-indol-5-ylamino)-thieno[3,2-b]pyridine-2-carboxylic acid pyridin-3-ylamideHCID 69737239—

Reaction Steps

The title compound was prepared from 2-methyl-1H-indol-5-ylamine and 7-chloro-thieno[3,2-b]pyridine-2-carboxylic acid pyridin-3-ylamide by a procedure analogous to Example 1C. MS: 400 (MH+), HPLC Rf: 4.58 min.; HPLC purity 99%.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06964961B2
Source datasetuspto-grants-2005_11
ORD IDord-8e93bf3acf36402eba7e1257c9135c41
Source noteuspto-grants-2005_11