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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1063169Generated: November 1, 2026

5-Amino-2-methylindole → [7-(2-Methyl-1h-indol-5-ylamino)-thieno[3,2-b]pyridin-2-yl]-morpholin-4-yl-methanone

https://huagongshe.com/reaction/1063169

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Amino-2-methylindoleHCID 2733992—
Reactant7-Chloro-thieno[3,2-b]pyridin-2-yl-morpholin-4-yl-methanoneHCID 22278622—
Product[7-(2-Methyl-1h-indol-5-ylamino)-thieno[3,2-b]pyridin-2-yl]-morpholin-4-yl-methanoneHCID 22278655—

Reaction Steps

The title compound was prepared from 2-methyl-1H-indol-5-ylamine and 7-chloro-thieno[3,2-b]pyridin-2-yl-morpholin-4-yl-methanone by a procedure analogous to Example 1C. MS: 393 (MH+), HPLC Rf: 3.90 min.; HPLC purity 96%.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06964961B2
Source datasetuspto-grants-2005_11
ORD IDord-033588b956e7473ba3b597c80336148a
Source noteuspto-grants-2005_11