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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1063171Generated: November 1, 2026

5-Amino-2-methylindole → 7-(2-Methyl-1h-indol-5-ylamino)-thieno[3,2-b]pyridine-2-carbonitrile

https://huagongshe.com/reaction/1063171

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Amino-2-methylindoleHCID 2733992—
Reactant7-Chlorothieno[3,2-B]pyridine-2-carbonitrileHCID 22278636—
Product7-(2-Methyl-1h-indol-5-ylamino)-thieno[3,2-b]pyridine-2-carbonitrileHCID 22278676—

Reaction Steps

The title compound was prepared from 2-methyl-1H-indol-5-ylamine and 7-chloro-thieno[3,2-b]pyridine-2-carbonitrile by a procedure analogous to Example 1C. MS: 305 (MH+), HPLC Rf: 4.86 min.; HPLC purity: 85%.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06964961B2
Source datasetuspto-grants-2005_11
ORD IDord-ea492e3343604397b8c24af2ed92cbf4
Source noteuspto-grants-2005_11