HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Amino-1-benzyl-3,5-dimethyl-3-ethylpiperidine → 4-Amino-3,5-dimethyl-3-ethylpiperidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Amino-1-benzyl-3,5-dimethyl-3-ethylpiperidine | HCID 10214591 | — |
| Catalyst | Palladium hydroxide | HCID 9942167 | — |
| Solvent | Methanol | HCID 887 | — |
| Solvent | HCID 178418361 | HCID 178418361 | — |
| Product | 4-Amino-3,5-dimethyl-3-ethylpiperidine | HCID 10125082 | — |
Reaction Steps
A mixture of 20% Pd(OH)2 on carbon (0.4 g) and 4-amino-1-benzyl-3,5-dimethyl-3-ethylpiperidine (2.2 g, 8.9 mmol) in methanol (15 ml) was stirred in hydrogen atmosphere (1 atm.) at 60° C. for 10 hr. The catalyst was filtered off, washed with methanol and filtrate was concentrated to dryness to afford 4-amino-3,5-dimethyl-3-ethylpiperidine as a semi solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06964966B2 |
| Source dataset | uspto-grants-2005_11 |
| ORD ID | ord-62b4dae9d9e4437ba20fb97ab8c32c6f |
| Source note | uspto-grants-2005_11 |