HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 4-(6-Bromo-hexyloxy)-piperidine hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 1,6-Dibromohexane | HCID 12368 | — |
| Reactant | Tert-butyl 4-hydroxypiperidine-1-carboxylate | HCID 643502 | — |
| Product | 4-(6-Bromo-hexyloxy)-piperidine hydrochloride | HCID 22279420 | — |
Reaction Steps
In analogy to example 1.2a and 1.3, reaction of 4-Hydroxy-piperidine-1-carboxylic-acid tert-butyl ester and 1,6-dibromohexane followed by treatment with 4N HCl yielded 4-(6-Bromo-hexyloxy)-piperidine hydrochloride, MS: 264 (MH+, 1Br).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06964974B2 |
| Source dataset | uspto-grants-2005_11 |
| ORD ID | ord-a9d1ea24796740e4bf9bb755c8222f0c |
| Source note | uspto-grants-2005_11 |