Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1063363Generated: November 1, 2026

1,5-Dibromopentane → HCID 10157489, compound

https://huagongshe.com/reaction/1063363

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,5-DibromopentaneHCID 8100—
ReactantPiperidin-4-olHCID 79341—
Reactant(2-Methoxyethyl)(methyl)amineHCID 300977—
Reactant4-Fluorophenylacetyl chlorideHCID 3744988—
ProductHCID 10157489HCID 10157489—

Reaction Steps

In analogy to example 1.2a, 1.3, 1.4 and 1.5, reaction of 4-Hydroxy-piperidine with 1,5-dibromopentane, (4-fluoro-phenyl)-acetyl chloride and N-(2-methoxyethyl)methylamine yielded 2-(4-Fluoro-phenyl)-1-(4-{5-[(2-methoxy-ethyl)-methyl-amino]-pentyloxy}-piperidin-1-yl)-ethanone, MS: 395 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06964974B2
Source datasetuspto-grants-2005_11
ORD IDord-3135edda1cc44ef18f9a748cd175a519
Source noteuspto-grants-2005_11