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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1063364Generated: November 1, 2026

1,5-Dibromopentane → HCID 10134150, compound

https://huagongshe.com/reaction/1063364

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,5-DibromopentaneHCID 8100—
ReactantPiperidin-4-olHCID 79341—
Reactant4-Fluorophenylacetyl chlorideHCID 3744988—
ReactantN-MethylcyclopropanamineHCID 11029756—
ProductHCID 10134150HCID 10134150—

Reaction Steps

In analogy to example 1.2a, 1.3, 1.4 and 1.5, reaction of 4-Hydroxy-piperidine with 1,5-dibromopentane, (4-fluoro-phenyl)-acetyl chloride and N-methylcyclopropylamine yielded 1-{4-[5-(Cyclopropyl-methyl-amino)-pentyloxy]-piperidin-1-yl}-2-(4-fluoro-phenyl)-ethanone, MS: 377 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06964974B2
Source datasetuspto-grants-2005_11
ORD IDord-a9c130b080d64a14b1101762a623411b
Source noteuspto-grants-2005_11