Tetrahydrothiophene → HCID 22280840, compound

To a 100 ml round bottom flask was sequentially added 10 mmol (1.69 g) of silver nitrate (AgNO3) and 20 ml of acetonitrile (CH3CN), followed by stirring at room temperature for 5 minutes. Next, 10 mmol (0.88 g, 0.88 ml) of tetrahydrothiophene was dropwise added to the flask by means of a syringe over 10 seconds and stirred at room temperature. After stirring for 30 minutes, the reaction mixture was warmed to 50° C. and further stirred for 30 minutes. Following cooling to room temperature, the reaction mixture was filtered through a microfilter and evaporated under vacuum to produce a white solid matter. 1H-NMR result in CD3CN is as follows: 2.01 (m, 4H), 2.98(m, 4H).

1. customTo a 100 ml round bottom flask was sequentially added
2. stirringstirred at room temperature
3. stirringAfter stirring for 30 minutes
4. temperaturethe reaction mixture was warmed to 50° C.
5. stirringfurther stirred for 30 minutes
6. temperatureFollowing cooling to room temperature
7. filtrationthe reaction mixture was filtered through a microfilter
8. customevaporated under vacuum
9. customto produce a white solid matter
10. custom1H-NMR result in CD3CN

ORD record

ord-fc76136311e840c48d02f6734dc3e990

Source dataset

uspto-grants-2005_11

DOI

10.6084/m9.figshare.5104873.v1

Patent number

US06965045B2