(4-Mercapto-5-methoxy-2-methyl-phenoxy)-acetic Acid Methyl Ester → {5-Methoxy-2-methyl-4-[5-(4-trifluoromethyl-phenyl)-isoxazol-3-ylmethylsulfanyl]-phenoxy}-acetic acid

HRID 1063697Notes

Reaction equation

HRID 1063697 reaction equation
Cl[CH2:2][C:3]1[CH:7]=[C:6]([C:8]2[CH:13]=[CH:12][C:11]([C:14]([F:17])([F:16])[F:15])=[CH:10][CH:9]=2)[O:5][N:4]=1.C[O:19][C:20](=[O:33])[CH2:21][O:22][C:23]1[CH:28]=[C:27]([O:29][CH3:30])[C:26]([SH:31])=[CH:25][C:24]=1[CH3:32]>>[CH3:30][O:29][C:27]1[C:26]([S:31][CH2:2][C:3]2[CH:7]=[C:6]([C:8]3[CH:13]=[CH:12][C:11]([C:14]([F:17])([F:16])[F:15])=[CH:10][CH:9]=3)[O:5][N:4]=2)=[CH:25][C:24]([CH3:32])=[C:23]([CH:28]=1)[O:22][CH2:21][C:20]([OH:33])=[O:19]

Participants

3

Reactant 2

HCID 11311052(4-Mercapto-5-methoxy-2-methyl-phenoxy)-acetic Acid Methyl EsterHCID 220642603-(Chloromethyl)-5-[4-(trifluoromethyl)phenyl]isoxazole

Product 1

HCID 10310542{5-Methoxy-2-methyl-4-[5-(4-trifluoromethyl-phenyl)-isoxazol-3-ylmethylsulfanyl]-phenoxy}-acetic acid

Procedure

The title compound was prepared in a manner analogous to Example 1F using 42C and 1D. MS m/z 468 (M+1).

Sources & evidence

ORD record
ord-3e5b61c3ddfa4745ade8f998926fd68f
Source dataset
uspto-grants-2005_11
Patent number
US06964983B2

Reaction notes

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