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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1063697Generated: November 1, 2026

(4-Mercapto-5-methoxy-2-methyl-phenoxy)-acetic Acid Methyl Ester → {5-Methoxy-2-methyl-4-[5-(4-trifluoromethyl-phenyl)-isoxazol-3-ylmethylsulfanyl]-phenoxy}-acetic acid

https://huagongshe.com/reaction/1063697

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(4-Mercapto-5-methoxy-2-methyl-phenoxy)-acetic Acid Methyl EsterHCID 11311052—
Reactant3-(Chloromethyl)-5-[4-(trifluoromethyl)phenyl]isoxazoleHCID 22064260—
Product{5-Methoxy-2-methyl-4-[5-(4-trifluoromethyl-phenyl)-isoxazol-3-ylmethylsulfanyl]-phenoxy}-acetic acidHCID 10310542—

Reaction Steps

The title compound was prepared in a manner analogous to Example 1F using 42C and 1D. MS m/z 468 (M+1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06964983B2
Source datasetuspto-grants-2005_11
ORD IDord-3e5b61c3ddfa4745ade8f998926fd68f
Source noteuspto-grants-2005_11