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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1063698Generated: November 2, 2026

(7-Mercapto-indan-4-yloxy)-acetic Acid Methyl Ester → {7-[5-(4-Trifluoromethyl-phenyl)-isoxazol-3-ylmethylsulfanyl]-indan-4-yloxy}-acetic acid

https://huagongshe.com/reaction/1063698

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(7-Mercapto-indan-4-yloxy)-acetic Acid Methyl EsterHCID 20770872—
Reactant3-(Chloromethyl)-5-[4-(trifluoromethyl)phenyl]isoxazoleHCID 22064260—
Product{7-[5-(4-Trifluoromethyl-phenyl)-isoxazol-3-ylmethylsulfanyl]-indan-4-yloxy}-acetic acidHCID 22280211—

Reaction Steps

The title compound was prepared in a manner analogous to Example 1F using 42C and 12C. MS m/z 464 (M+1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06964983B2
Source datasetuspto-grants-2005_11
ORD IDord-65fed0704b3342b68c04984bb64a1f7c
Source noteuspto-grants-2005_11