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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1063705Generated: October 30, 2026

(7-Mercapto-indan-4-yloxy)-acetic Acid Methyl Ester → {7-[3-(5-Trifluoromethyl-pyridin-2-yl)-benzylsulfanyl]-indan-4-yloxy}-acetic acid

https://huagongshe.com/reaction/1063705

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(7-Mercapto-indan-4-yloxy)-acetic Acid Methyl EsterHCID 20770872—
Reactant2-(3-Chloromethyl-phenyl)-5-trifluoromethyl-pyridineHCID 22280160—
Product{7-[3-(5-Trifluoromethyl-pyridin-2-yl)-benzylsulfanyl]-indan-4-yloxy}-acetic acidHCID 22280108—

Reaction Steps

The title compound was prepared in the manner analogous to Example 1F using 12C and 53B. MS m/z 474 (M+1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06964983B2
Source datasetuspto-grants-2005_11
ORD IDord-1a6a325aa2954912bdc5c73dc1d51d44
Source noteuspto-grants-2005_11