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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1063748Generated: November 2, 2026

(8-Mercapto-chroman-5-yloxy)-acetic acid methyl ester → {8-[4-(2,5-Dichloro-benzyloxy)-benzylsulfanyl]-chroman-5-yloxy}-acetic Acid

https://huagongshe.com/reaction/1063748

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(8-Mercapto-chroman-5-yloxy)-acetic acid methyl esterHCID 11288267—
Reactant1,4-Dichloro-2-(4-chloromethyl-phenoxymethyl)-benzeneHCID 22280050—
Product{8-[4-(2,5-Dichloro-benzyloxy)-benzylsulfanyl]-chroman-5-yloxy}-acetic AcidHCID 22280019—

Reaction Steps

The title compound was prepared in the manner analogous to Example 1F using (8-mercapto-chroman-5-yloxy)-acetic acid methyl ester and 1,4-Dichloro-2-(4-chloromethyl-phenoxymethyl)-benzene prepared in the manner analagous to Example 71A. m/z 519 (M+1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06964983B2
Source datasetuspto-grants-2005_11
ORD IDord-a4649d73aaf44738a61f179c5e77a7bb
Source noteuspto-grants-2005_11