反应详情

The title compound was prepared in the manner analogous to Example 1 using 85A. mp 98-100° C.; IR (KBr) cm−1: 3038, 2854, 1729, 1508, 1240, 1124; 400 MHz 1H NMR (DMSO-d6): δ 12.95 (br(s), 1H), 7.57-7.62 (m, 1H), 7.39-7.53 (m, 2H); 7.12-7.20 (m, 2H), 6.84-6.96 (m, 3H), 6.26 (d, 1H, J=8.6 Hz), 5.05 (s, 2H), 4.58 (s, 2H), 4.09 (t, 2H, J=4.9 Hz), 3.92 (s, 2H), 2.55 (t, 2H, J=6.5 Hz), 1.83 (pentet, 2H); MS m/z 503 (M−1). Anal. Calc'd for C25H22Cl2O5S: C, 59.41; H, 4.39. found: C, 59.20; H, 4.20.